National Repository of Grey Literature 4 records found  Search took 0.00 seconds. 
New modified 7-deazapurine bases and nucleosides
Krömer, Matouš ; Hocek, Michal (advisor) ; Smrček, Stanislav (referee)
The three ways of synthesis of 5'-deoxy and 5'deoxy-5'-fluoromodified nucleosides derived from known cytostatic compounds was designed. Two routes were successfully developed and target substances were prepared. Third one was unsuccessful due to difficulties with deprotection of the key intermediate.
New modified 7-deazapurine bases and nucleosides
Krömer, Matouš ; Hocek, Michal (advisor) ; Smrček, Stanislav (referee)
The three ways of synthesis of 5'-deoxy and 5'deoxy-5'-fluoromodified nucleosides derived from known cytostatic compounds was designed. Two routes were successfully developed and target substances were prepared. Third one was unsuccessful due to difficulties with deprotection of the key intermediate.

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